Diagnosis of dementia with Lewy bodies: diagnostic performance of combined 123I-IMP brain perfusion SPECT and 123I-MIBG myocardial scintigraphy

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Diagnosis of dementia with Lewy bodies: diagnostic performance of combined 123I-IMP brain perfusion SPECT and 123I-MIBG myocardial scintigraphy

OBJECTIVE We assessed the value of combining (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy for the discrimination of dementia with Lewy bodies (DLB) from other types of dementia. METHODS We subjected 252 consecutive patients with clinically suspected DLB to both (123)I-IMP brain perfusion SPECT and (123)I-MIBG myocardial scintigraphy. Patients with Parkinson's disea...

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123I-ioflupane brain SPECT and 123I-MIBG cardiac planar scintigraphy combined use in uncertain parkinsonian disorders

We evaluated the clinical usefulness of the combined use of I-ioflupane brain single photon emission computed tomography (SPECT) and I-metaiodobenzylguanidine (MIBG) cardiac scintigraphy in discriminating uncertain parkinsonism with vascular lesions in striatal nuclei at magnetic resonance imaging (MRI). Forty-three consecutive patients with uncertain parkinsonism and vascular lesions at MRI in...

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Diagnostic Accuracy of 123I-Meta-Iodobenzylguanidine Myocardial Scintigraphy in Dementia with Lewy Bodies: A Multicenter Study

BACKGROUND AND PURPOSE Dementia with Lewy bodies (DLB) needs to be distinguished from Alzheimer's disease (AD) because of important differences in patient management and outcome. Severe cardiac sympathetic degeneration occurs in DLB, but not in AD, offering a potential system for a biological diagnostic marker. The primary aim of this study was to investigate the diagnostic accuracy, in the ant...

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Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies.

BACKGROUND (123)I-FP-CIT SPECT (single photon emission computed tomography) can help in the differential diagnosis of probable dementia with Lewy bodies (Lewy body dementia) and Alzheimer's disease. AIMS Our aim was to determine the accuracy of (123)I-FP-CIT SPECT in diagnosing people with possible dementia with Lewy bodies. METHOD We undertook a 12-month follow-up of 325 individuals with p...

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123I-MIBG myocardial scintigraphy in patients with "takotsubo" cardiomyopathy.

UNLABELLED The clinical characteristics of reversible left ventricular dysfunction due to "takotsubo" cardiomyopathy have been described, but the origin of this condition remains unclear. This study investigated (123)I-metaiodobenzlguanidine ((123)I-MIBG) myocardial scintigraphy in patients with takotsubo cardiomyopathy. METHODS Eight consecutive patients with takotsubo cardiomyopathy were st...

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ژورنال

عنوان ژورنال: Annals of Nuclear Medicine

سال: 2013

ISSN: 0914-7187,1864-6433

DOI: 10.1007/s12149-013-0796-3